Prof. Jungjoon Kempthorne Lee

Assistant Professor

National University of Singapore

jjk.lee@nus.edu.sg

Dr. Jungjoon Lee is an assistant professor of Biochemistry and Synthetic Biology for Clinical and Technological Innovation at the National University of Singapore. He trained in chemistry, structural biology, and directed evolution at the University of Cambridge and Stanford University. He previously served as a senior researcher in biotherapeutics at the Samsung Advanced Institute of Technology, where he received the Multiple Citizenship for Outstanding Talent award from the Korean Ministry of Justice, and later led CRISPR platform development at Toolgen, contributing to key patents, publications, and the company’s IPO on KOSDAQ. He is a founding member and former vice chairman of the Korean Association for Genome Editing and currently serves as Vice President Membership of the NUSS Toastmasters Club.

Research Interest

Advancement of platform technologies for genome editing and broadening their applications.

Publications

Selected Publications

  • Young-hoon Kim, Nahye Kim, Ikenna Okafor, Sungchul Choi, Seonwoo Min, Joonsun Lee, Seung-Min Bae, Keunwoo Choi, Janice Choi, Vinayak Harihar, Youngho Kim, Jin-Soo Kim, Benjamin Kleinstiver, Jungjoon K. Lee*, Taekjip Ha*, Hyongbum Henry Kim*, Sniper2L is ahigh-fidelity Cas9 variant with high activity, Nature Chemical Biology, 2023, https://doi.org/10.1038/s41589-023-01279-5.
  • Jeonghun Kwon, Minyoung Kim, Woochang Hwang, Anna Jo, Gue-Ho Hwang, Minhee Jung, Un Gi Kim, Gang Cui, Heonseok Kim, Joon-Ho Eom, Junho K. Hur, Junwon Lee, Youngho Kim, Jin-soo Kim, Sangsu Bae, Jungjoon K. Lee*, Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches, Genome Biology, 2023, 24, Article number: 4.
  • Jeonghun Kwon, Minyoung Kim, Seungmin Bae, Anna Jo, Youngho Kim, Jungjoon K. Lee*,TAPE-seq is a cell-based method for predicting genome-wide off-target effects of prime editor, Nature Communications, 2022, 13, Article number: 7975
  • Ikenna C Okafor, Digvijay Singh, Yanbo Wang, Minhee Jung, Haobo Wang, John Mallon, Scott Bailey, Jungjoon K. Lee, Taekjip Ha*, Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding, Nucleic Acids Res. 2019 Dec 16; 47(22): 11880–11888
  • Jungjoon K. Lee*, Euihwan Jeong, Joonsun Lee, Minhee Jung, Eunji Shin, Young-hoon Kim,Kangin Lee, Inyoung Jung, Daesik Kim, Seokjoong Kim & Jin-Soo Kim*, Directed evolution ofCRISPR-Cas9 to increase its specificity, Nature Communications, 2018; 9, Article number: 3048.

Principal Investigators

Prof. Yong-Su Jin

Director of Research (Future Foods); Illinois ARCS Professor of Food Microbiology

University of Illinois Urbana-Champaign
Prof. Wen Shan Yew

Associate Professor, Biochemistry

National University of Singapore
Prof. Michael Miller

Professor of Food Microbiology

University of Illinois Urbana-Champaign
Prof. Vijay Singh

Founder Professor, Agricultural and Biological Engineering; Director, Integrated Bioprocessing Research Laboratory

University of Illinois Urbana-Champaign
Prof. Jeremy Guest

Department Head, David C. Crawford Faculty Scholar; Professor, Department of Civil & Environmental Engineering

University of Illinois Urbana-Champaign
Prof. Christopher Rao

Ray and Beverly Mentzer Professor; Dept Head, Chemical & Biomolecular Engineering

University of Illinois Urbana-Champaign
Prof. Ting Lu

Professor, Bioengineering

University of Illinois Urbana-Champaign
Prof. Huimin Zhao

Steven L. Miller Chair, Professor, Chemical & Biomolecular Engineering

University of Illinois Urbana-Champaign
Prof. Na Wei

Associate Professor, Civil & Environmental Engineering

University of Illinois Urbana-Champaign
Prof. Dong Wang

Professor and Associate Dean for Research

University of Illinois Urbana-Champaign
Prof. Yalin Li

Assistant Professor, Department of Civil and Environmental Engineering

Rutgers University
Prof. Chueh Loo Poh

Associate Professor, Biomedical Engineering

National University of Singapore
Prof. Matthew Chang

Associate Professor, Biomedical Engineering

National University of Singapore
Prof. Shao Quan Liu

Associate Professor, Food Science & Technology

National University of Singapore
Prof. Susanna Leong

Vice President, Applied Research; Professor

Singapore Institute of Technology
Prof. Won Jae Choi

Associate Professor; Deputy Cluster Director, Food Chemical and Biotechnology

Singapore Institute of Technology
Prof. In Young Hwang

Associate Professor, Food, Chemical and Biotechnology

Singapore Institute of Technology
Prof. Bin Cao

Associate Chair (Research); Associate Professor, School of Civil and Environmental Engineering

Washington State University
Dr. Ee Lui Ang

Department Head, Strain Engineering

A*STAR Singapore Institute of Food and Biotechnology Innovation(A*STAR SIFBI)
Dr. Uttam Surana

Research Director, Institute of Molecular and Cell Biology

Agency for Science, Technology and Research (A*STAR)
Dr. Louise F.H. Funke

Lee Kuan Yew Postdoctoral Fellow, Biomedical Engineering

National University of Singapore
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